Chinese Taipei's world number seven Lin Yun-Ja was the first victim of an upset loss on day two of the World Table Tennis Macao event, in a five-set defeat to China's Fang Bo.
The teenager suffered a defeat in the men's singles Battle Two round, with the world number 248 Fang now progressing to the quarter-finals after an 11-7, 11-10, 2-11, 10-11, 13-11 win.
Despite taking a two-set lead, Fang was pegged back by the young prodigy who stormed the third set before eking out the fourth set.
However Fang's forehands in the final set were enough to secure a famous win.
His biggest accolade to date is a silver medal in the men's singles at the 2018 China National Table Tennis Championships, regarded as the most competitive national championships in the sport.
South Korea's Jeoung Young-sik also won in five sets against England's Liam Pitchford in a back-and-forth battle by a score of 6-11, 11-8, 11-8, 9-11, 11-5.
Two women's singles Battle Two matches took place too - with Chinese Taipei's Cheng I-Ching defeating China's Liu Weishan in another five set match that was concluded in just 31 minutes.
Cheng found a way past with a late block and counter in the final set to help the world number eight progress to the final eight.
Earlier, world number 13 Chen Xingtong of China made quick work of Hong Kong's Doo Hoi Kem in straight sets to progress too.
In the evening session, the top four seeds in both singles competitions faced off to determine who they wished to play in the next round, with winners receiving a preferential draw.
In the quick five-point sets, Wang Manyu defeated her Chinese compatriot world number one Chen Meng, while another all-Chinese contest was settled after Ding Ning got the better of Sun Yingsha.
In the men's singles top four seed battle, China's Lin Gaoyuan defeated Brazil's Hugo Calderano in five sets after being down by two; while in another all-Chinese encounter, Xu Xin won in maximum sets against Ma Long.
Taking place in the Tap Seac Multisport Complex in the Chinese territory of Macau, the event is set to finish on Sunday (November 29).