The three riders attacked from the peloton just before the top of the Alto de La Lora climb with six kilometres to go, managing to hold off the chasing pack in the final minutes.

Stage one saw riders cover 100 kilometres from Villadiego to Sargentes de la Lora.

Five seconds after the top three finished, Cuba's Arlenis Sierra of A.R. Monex led home a small peloton to take fourth.

"We had a team plan where we wanted to first try to split the race in the crosswinds," said Brown.

"Our team worked really well to do that, the peloton split there, and it put a lot of teams under pressure and hurt the legs a little bit before coming into the finale.

"Then my team did an awesome lead-out to the bottom of the climb.

"I just sat in on the climb and waited until we got near the top, and that's where I launched my attack."

It was the first time the Vuelta a Burgos Feminas was an International Cycling Union (UCI) Women's WorldTour race, having previously acted as a national race in Spain for four years before becoming a UCI-affiliated race in 2019.

Italians Soraya Paladin and Sofia Bertizzolo of Liv Racing and Elisa Longo Borghini of Trek-Segafredo were fifth to seventh, while Dutch riders and title candidates Demi Vollering of SD Worx and Annemiek van Vleuten of Movistar made the top 10.

Anna van der Breggen was part of the pack too, keeping herself in contention for the overall title.